Its effects often last for 4 to 5 hours. It might work longer if you have mild to moderate erectile dysfunction. This medicine also works best when you take it an hour before sex on an empty stomach.
Each oral medicine for ED has a slightly different chemical makeup. These small differences affect the way each medication works, such as how quickly it takes effect and wears off, and the possible side effects. Your doctor or other health care professional can recommend one for you based on these factors, other health conditions you have and any other medicines you take. This medicine works best when you take it on an empty stomach an hour before sex. The body takes longer to absorb it after a high-fat meal or alcohol. As with sildenafil, a high-fat meal or alcohol keep the body from absorbing it as quickly. Vardenafil usually works for 4 to 5 hours. Its effects might last longer if you have mild to moderate ED. A newer form of the medicine that dissolves on the tongue might work faster than the pill that you swallow. This medication is taken with or without food an hour before sex.
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Cialis Soft Tabs | 20mg | 10 Pills | 39.03€ 37.17€ | |
| Viagra Original | 100mg | 4 Pills | 40.94€ 38.99€ | |
| Cialis Soft Tabs | 20mg | 60 + 4 Pills | 159.37€ 151.78€ | |
| Cialis Professional | 20mg | 270 + 6 Pills | 623.07€ 593.40€ | |
| Levitra Generic | 60mg | 20 Pills | 81.30€ 77.43€ | |
| Super Kamagra | 160 mg | 92 + 6 Pills | 478.75€ 455.95€ | |
| Viagra Generic | 50mg | 360 + 10 Pills | 225.33€ 214.60€ | |
| Cialis Generic | 40mg | 180 + 10 Pills | 277.29€ 264.09€ | |
| Levitra Generic | 40mg | 120 + 8 Pills | 302.37€ 287.97€ | |
| Levitra Professional | 20mg | 180 + 4 Pills | 502.31€ 478.39€ | |
| Cialis Generic | 10mg | 270 + 10 Pills | 308.71€ 294.01€ | |
| Cialis Professional | 20mg | 30 Pills | 104.57€ 99.59€ | |
| Viagra Generic | 100mg | 360 + 10 Pills | 330.21€ 314.49€ | |
| Priligy Generic Dapoxetine | 60mg | 120 + 10 Pills | 341.26€ 325.01€ | |
| Apcalis SX Oral Jelly | 20mg | 30 + 5 Sachets | 141.84€ 135.09€ | |
| Viagra Generic | 25mg | 90 + 6 Pills | 105.03€ 100.03€ |
It works for up to 36 hours.
A single-centre result of two courses of low-intensity shockwave therapy (Li-SWT) in erectile dysfunction. Effect of oral administration of high-dose nitric oxide donor L-arginine in men with organic erectile dysfunction: results of a double-blind, randomized, placebo-controlled study. Treatment of erectile dysfunction with pycnogenol and L-arginine. Journal of Sex & Marital Therapy, 29(3), 207–213. Red ginseng for treating erectile dysfunction: a systematic review.
British Journal of Clinical Pharmacology, 66(4), 444-450. The World Journal of Men's Health, 36(3), 183-191. Efficacy and safety of long-term tadalafil 5 mg once daily combined with sildenafil 50 mg as needed at the early stage of treatment for patients with erectile dysfunction. Phosphodiesterase-5 (PDE5) Inhibitors In the Management of Erectile Dysfunction. The Efficacy and Safety of Avanafil During a Treatment of Male Erectile Dysfunction: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Therapeutics and Clinical Risk Management, 19, 629-644. The efficacy of fluoxetine in the treatment of premature ejaculation: a double-blind placebo controlled study. The Journal of Urology, 156(5), 1631–1632. Relative Efficacy of Minoxidil and the 5-α Reductase Inhibitors in Androgenetic Alopecia Treatment of Male Patients: A Network Meta-analysis. Atorvastatin efficacy in the primary and secondary prevention of cardiovascular events. You can take it in a small dose daily or in a larger dose as needed. You can take this medicine with or without food 30 minutes before sex, depending on the dose. It lasts 4 to 5 hours, or longer if you have mild to moderate ED. These medicines all work well for ED. When choosing one, tell your doctor or other health care professional what your preferences are, such as cost, ease of use, how long the drug's effects last and side effects. Generic versions of sildenafil, vardenafil and tadalafil are available. Check with your health care team before you take any medicine for erectile dysfunction. Oral ED medicines might not work or might be dangerous if you also take any of the following: Often, these are prescribed for chest pain called angina. Some examples of nitrates are nitroglycerin (Nitro-Dur, Nitrostat, others), isosorbide mononitrate (Monoket) and isosorbide dinitrate (Bidil). These are commonly prescribed for an enlarged prostate or male pattern baldness. They include dutasteride (Avodart, Jalyn) and finasteride (Propecia, Proscar). Medicines that block an enzyme called CYP3A4. Oral medicine for ED also might not be safe or work well if you have: Very low blood pressure, called hypotension, or uncontrolled high blood pressure, called hypertension. Kidney disease that needs to be treated with dialysis. These include a heart attack, stroke or a serious heart rhythm disorder in the past six months. An inherited eye disease that affects the retina.
| Medication | Success Rate (%) | Average Onset (minutes) | Duration (hours) |
|---|---|---|---|
| Sildenafil | 70 | 30-60 | 4-6 |
| Tadalafil | 75 | 30 | Up to 36 |
| Vardenafil | 68 | 25-60 | 4-5 |
| Avanafil | 80 | 15-30 | 6-12 |
Side effects of oral ED medicines are often mild.
Trends in Urology & Men's Health, 12(6), 19-22. Psychological Factors Related to Impotence as a Sexual Dysfunction in Young Men: A Literature Scan for Noteworthy Research Frameworks. Clinics and Practice, 12(4), 501-512. The role of cortisol in erectile function. Translational Andrology and Urology, 12(8), 1213-1214.
People who Expect to Enter Psychotherapy are Prone to Believing that They Have Forgotten Memories of Childhood Trauma and Abuse. Mental Health Medications, U.S. Department of Health and Human Services. Penile Entrapment With Thick Penile Ring: A Case Report and Literature Review. Vacuum therapy in erectile dysfunction—Science and clinical evidence.
International Journal of Impotence Research, 22(4), 211-219. The science of vacuum erectile device in penile rehabilitation after radical prostatectomy. Translational Andrology and Urology, 2(1), 61–66. The role of vacuum pump therapy to mechanically straighten the penis in Peyronie’s disease. Maca (L. Visual changes, such as blue tinge to vision, sensitivity fildena 150 mg tablet to light or blurred sight.
Rarely, more-serious side effects can happen, including: Some people have suddenly lost some of their hearing or vision after taking one of these medicines. But it isn't clear whether these side effects were caused by the medicine or by health conditions that the people already had. Get medical care right away if you take oral ED medicine and have sudden loss of hearing or vision. An erection that doesn't go away on its own. Called priapism, this rare condition can be painful. You need to get treatment for it as soon as possible to help prevent damage to your penis. If you have an erection that lasts more than four hours, call your care team right away.
| Factor | Impact on Tablets | Advice |
|---|---|---|
| Smoking | Reduced blood flow | Quit smoking for better results |
| Alcohol Consumption | Can diminish effectiveness | Limit alcohol intake |
| Obesity | Impaired blood circulation | Maintain healthy weight |
| Stress | Affects libido and response | Practice stress-reducing techniques |
| Exercise | Improves cardiovascular health | Regular physical activity |
Treatments for erectile dysfunction are big business, and online scams abound. If you do buy medicines over the internet: Check to see if an online pharmacy is legitimate. Never order medicines from an online pharmacy that doesn't list its phone number and physical address, has prices that seem too good to be true, or tells you that no prescription is needed. Also stay away from ones that don't have a licensed pharmacist on staff to answer your questions. Some illegal businesses sell fake versions of real medicines, which can be dangerous or might not work.
In the United States, the National Association of Boards of Pharmacy can tell you whether an online pharmacy is licensed and in good standing. If you live in another country, check to see if pharmacy association or regulation agencies offer services like these. Make sure you get the right prescription and dose. When you order medicines and when you receive them in the mail, make sure they're the exact dose and type prescribed by your doctor or other health care professional. The dose is the amount of medicine you take. Don't be fooled into buying "herbal viagra." Never take any medicines that claim to be the "herbal" or nonprescription version of an oral medicine for ED. These aren't an effective option, and some contain harmful substances.
meyenii) for improving sexual function: a systematic review. BMC Complementary and Alternative Medicine, 10, 44. Effect of Tongkat Ali on stress hormones and psychological mood state in moderately stressed subjects. Journal of the International Society of Sports Nutrition, 10(1), 28. An investigation into the stress-relieving and pharmacological actions of an vardenafil vilitra 60 mg ashwagandha (Withania somnifera) extract: A randomized, double-blind, placebo-controlled study.
A Randomized, Double-Blind, Placebo-Controlled, Crossover Study Examining the Hormonal and Vitality Effects of Ashwagandha ( Withania somnifera) in Aging, Overweight Males. American Journal of Men's Health, 13(2), 1557988319835985. Effect of standardized root extract of ashwagandha (Withania somnifera) on well-being and sexual performance in adult males: A randomized controlled trial. Subjective effects of Lepidium meyenii (Maca) extract on well-being and sexual performances in patients with mild erectile dysfunction: a randomised, double-blind clinical trial. Comprehensive Intersystemic Assessment Approach to Relieve Psychogenic Erectile Dysfunction: A Review.
Open Access Macedonian Journal of Medical Sciences, 9(F), 189–196. The Journal of Sexual Medicine, 7(4 Pt 1), 1518–1528. Oxytocin in the Treatment of Psychiatric Disorders. Efficacy and safety of fixed-dose oral sildenafil in the treatment of erectile dysfunction of various etiologies. Efficacy and safety of avanafil for treating erectile dysfunction: results of a multicentre, randomized, double-blind, placebo-controlled trial. Our caring team of Mayo Clinic experts can help you with your health concerns. Visit Mayo Clinic Men's Health to get started. The most common sexual dysfunctions in men include lack of interest, premature ejaculation and erectile dysfunction.
Medicines that you take by mouth are called oral medicines. They're often the first line of treatment for trouble getting or keeping an erection, called erectile dysfunction (ED). Oral medicines for ED usually work well and cause few side effects. The four main medicines taken by mouth for erectile dysfunction are: They enhance the effects of a chemical the body makes that relaxes muscles in the penis, called nitric oxide. This boosts blood flow and helps you get an erection from sexual activity. The latter affects 52% of men between the ages of 40 and 70, including mild, moderate and complete forms of ED. Organic or physical causes for sexual dysfunction in men include vascular, hormonal and neurologic factors. Concerning vascular causes, the risk factors for atherosclerosis (including smoking, high blood pressure, diabetes (diabetics do not respond well to pills like sildenafil (Viagra)) and high cholesterol are ALSO risk factors for erectile dysfunction. Since a straddle injury or use of a narrow saddle can obstruct and impair arteries to the penis, bicycle riding is also considered a risk factor for erectile dysfunction.