7 DRUG INTERACTIONS

Sildenafil > sildenafil 12.5 mg


HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all

Dosing & Uses

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What happens if I take too much sildenafil?

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See full prescribing information for SILDENAFIL INJECTION.SILDENAFIL injection, for intravenous useInitial U.S.

Side Effects

For pulmonary hypertension, take a missed dose as soon as you remember it. If it’s almost time for the next dose, skip the missed dose and take the next dose as scheduled. If too much sildenafil is taken, get immediate medical attention. Side effects of sildenafil, such as headache, flushing, stomach upset, nasal congestion, back pain, low blood pressure, or painful erections (priapism), are more likely and sildenafil 25 mg tablets could be worse than normal. Serious side effects are also possible such as heart rate problems, chest pain (angina), and heart attack.

Warnings for people with certain health conditions

Do not take sildenafil if you are using medications called nitrates, such as nitroglycerin, or over-the-counter nitrites (“poppers”), such as amyl nitrite. Sildenafil should also never be combined with heart failure drugs called guanylate cyclase stimulators (riociguat or vericiguat). Make sure the prescriber knows about all drugs and substances you use, including vitamins, supplements, and illicit substances. To avoid more serious drug interactions, the prescriber will need to know about: Other ED drugs or supplements, particularly Cialis (tadalafil) or vardenafil Other ED drugs or supplements, particularly Cialis (tadalafil) or vardenafil HIV/AIDS drugs called protease inhibitors, especially ritonavir HIV/AIDS drugs called protease inhibitors, especially ritonavir Oral antifungal drugs such as ketoconazole or itraconazole Oral antifungal drugs such as ketoconazole or itraconazole To reduce the risk of side effects, avoid drinking grapefruit juice when taking sildenafil. Although there isn’t much information about the safety of sildenafil during pregnancy, animal studies have shown no adverse effects on a fetus. Approval: 1998INDICATIONS AND USAGEAdultsSildenafil injection is a phosphodiesterase-5

More about sildenafil

Pharmacy names, logos, brands, and other trademarks are the property of their respective owners. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911. If you are a consumer or patient please visit this version. (PDE-5) inhibitor indicated for the treatment of pulmonary arterial

  • Sildenafil 12.5 mg is a lower dose used for mild erectile dysfunction.
  • It helps relax blood vessels to increase blood flow.
  • Often prescribed when starting treatment or for lighter symptoms.

hypertension (PAH) (World Health Organization [WHO] Group I) in

5.5 Hearing Loss

Do not freeze.Throw away any unused medicine 60 days after receiving it from the pharmacist or on the expiration date written on the bottle’s label. How to take sildenafil oral suspension for pulmonary hypertension: Please read and follow the Instructions for Use. Please read and follow the Instructions for Use. Do not use the medicine if it’s still in powder form, doesn’t have a bottle adapter, or is missing an oral syringe. The pharmacist can provide a bottle adapter or oral syringe.

Drug Interactions

Shake the bottle well for at least 10 seconds. Always measure the dose with the oral syringe provided in the package. Do not mix the dose with other liquids or flavorings. The person getting the medicine should be upright. Place the syringe in the mouth against the cheek. adults to improve exercise ability and delay clinical worsening.

  • Store sildenafil at room temperature, away from moisture and heat.
  • Keep out of reach of children and pets.
  • Do not use expired medication; freshness ensures safety and efficacy.

(1)DOSAGE AND ADMINISTRATIONInjection (Adults): 10 mg three times a day

Possible Alternatives to Sildenafil

Wash the syringe with water and allow it to dry after each use. Store sildenafil oral suspension in the refrigerator. Throw away any unused medicine 60 days after receiving it from the pharmacist or on the expiration date written on the bottle’s label. In clinical trials, sildenafil showed significant effects on erectile response 60 minutes after the dose was taken, though the effects may be evident within 30 minutes. For pulmonary hypertension, sildenafil lowers blood pressure about one to two hours after a dose is taken.

Dosage for pulmonary arterial hypertension (PAH)

With a half-life of four hours, sildenafil and its active metabolite are completely cleared from the system in about 20 hours, though the effects fade before then. For erectile dysfunction, sildenafil produces its maximum effects for about two hours and can still produce an erectile response four hours after a dose is taken. For pulmonary hypertension, sildenafil’s benefits in lowering blood pressure were the same as a placebo (inert pill) after eight hours. For treatment of erectile dysfunction, take only one dose per day. If a dose has been forgotten, take it when remembered but wait at least 30 minutes before attempting sexual activity. administered as an intravenous bolus injection (2.1)DOSAGE FORMS AND STRENGTHSInjection: 10

Common Side Effects Severity Management Tips
Headache Mild Hydration, pain relief as needed
Flushing Mild Cool environment, focus on gradual temperature changes
Nasal Congestion Mild Use of decongestants if necessary
Dyspepsia Mild Taking medication with food or avoiding fatty foods

mg/12.5 mL in a single-dose vial (3)CONTRAINDICATIONSWARNINGS AND PRECAUTIONSVasodilation effects may be more common in patients with hypotension or on antihypertensive therapy.

  • This dose is often used as a starting point before increasing if needed.
  • Combining with high-fat meals may slow absorption.
  • Avoid grapefruit juice, as it can affect sildenafil metabolism.

(5.1)Use in pulmonary veno-occlusive disease (PVOD) may cause pulmonary edema and is not recommended.

5.1 Hypotension

Pregnant women or women who are breastfeeding should ask for medical advice before taking sildenafil. Plumb’s Veterinary Drug Manual, 7 edition Plumb’s Veterinary Drug Manual, 7 edition Revatio prescribing information, DailyMed (NIH National Library of Medicine) Revatio prescribing information, DailyMed (NIH National Library of Medicine) Sildenafil citrate powder for oral suspension prescribing information, DailyMed (NIH National Library of Medicine) Sildenafil citrate powder for oral suspension prescribing information, DailyMed (NIH National Library of Medicine) Systemic and pulmonary hypertension in dogs and cats, Merck Veterinary Manual Systemic and pulmonary hypertension in dogs and cats, Merck Veterinary Manual Viagra drug summary, Prescriber’s Digital Reference (PDR) Viagra drug summary, Prescriber’s Digital Reference (PDR) Viagra sildenafil citrate tablet prescribing information, DailyMed (NIH National Library of Medicine) Viagra sildenafil citrate tablet prescribing information, DailyMed (NIH National Library of Medicine) Jessica Swirble, Pharm.D., is a 2007 graduate of the Philadelphia College of Pharmacy and has more than 16 years of experience as a pharmacist. She currently resides in Pennsylvania and works as a community pharmacist. She is also a freelance medical writer and reviewer. When away from work, she enjoys traveling, baking, reading, and spending time with her family.

Drugs you should not use with sildenafil

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Point Explanation Advice
Timing for ingestion Take 30-60 minutes before sexual activity Avoid late ingestion
Alcohol consumption May increase side effects Limited alcohol intake
Food intake Can be taken with or without food Avoid high-fat meals for quicker onset
Adherence to prescribed dose Important for safety and efficacy Follow doctor's instructions

sudden decrease or loss of vision or hearing occurs.

Rights and permissions

Allow at least 24 hours between doses.Store sildenafil tablets at room temperature. Take the prescribed dose about one hour before you have sex. The dose can be taken one-half hour to four hours before sexual activity. Do not take more than one dose a day. Allow at least 24 hours between doses.

Is 20 mg of sildenafil effective for ED?

For pulmonary arterial hypertension:Take or administer the prescribed dose three times a day, four to six hours apart. Take or administer the prescribed dose three times a day, four to six hours apart. How to take sildenafil oral suspension for pulmonary hypertension:Please read and follow the Instructions for Use.Do not use the medicine if it’s still in powder form, doesn’t have a bottle adapter, or is missing an oral syringe. The pharmacist can provide a bottle adapter or oral syringe.Shake the bottle well for at least 10 seconds.Always measure the dose with the oral syringe provided in the package.Do not mix the dose with other liquids or flavorings.The person getting the medicine should be upright.Place the syringe in the mouth against the cheek. Push the plunger completely down.Wash the syringe with water and allow it to dry after each use.Store sildenafil oral suspension in the refrigerator.