Choosing which is better can depend on personal preferences and how often you plan to be intimate. Cialis may work faster and have effects that last longer than vardenafil. In addition, Cialis may be preferred by those who also have BPH or want a once-daily option. It’s best to consult a doctor for medical advice about the best option for you. Taking Levitra or Cialis along with alcohol may increase the chances of side effects.
| Quantity Purchased | Price per Tablet (USD) | Total Cost (USD) | Savings % |
|---|---|---|---|
| 10 tablets | $2.75 | $27.50 | 0% |
| 30 tablets | $2.40 | $72.00 | 13% |
| 60 tablets | $1.80 | $108.00 | 35% |
| 90 tablets | $1.50 | $135.00 | 45% |
Since alcohol affects blood vessels in a way similar to these medications, you might experience more noticeable symptoms, like flushing and dizziness. While small amounts of alcohol might be okay, drinking too much can make these medications less effective.
PDE5 inhibitors can increase the risk of dangerously low blood pressure, particularly when combined with other blood pressure medications. It is important to monitor blood pressure regularly if you are prescribed these drugs. If you experience priapism, or a painful erection that lasts longer than 4 hours, seek emergency medical attention. Priapism can cause libido for women damage to the penile tissue if it’s not treated promptly. Visual problems, such as sudden vision loss, are rare adverse effects of vardenafil and Cialis.
Using these medications can also increase the risk of a sudden decrease or loss of hearing. Seek prompt medical attention if you experience these effects. Levitra and Cialis belong to the same class of drugs called PDE5 inhibitors, but they are not the same drugs. These drugs contain different active ingredients and can be used in different ways. Cialis is available as a once-daily pill, while Levitra is only taken as needed. Talk to a doctor about how much alcohol is safe to drink while using these medicines. There is no single ED drug that is considered the best.
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Kamagra Oral Jelly | 100 mg | 30 + 5 Sachets | 136.20€ 129.71€ | |
| Viagra Original | 100mg | 64 + 4 Pills | 264.15€ 251.57€ | |
| Cialis Original | 20mg | 34 + 2 Pills | 183.99€ 175.23€ | |
| Priligy Generic Dapoxetine | 60mg | 30 + 6 Pills | 106.65€ 101.57€ | |
| Cialis Original | 20mg | 92 + 4 Pills | 377.99€ 359.99€ | |
| Cialis Professional | 20mg | 20 Pills | 78.33€ 74.60€ | |
| Levitra Original | 20mg | 76 + 4 Pills | 344.39€ 327.99€ | |
| Viagra Generic | 200mg | 360 + 10 Pills | 481.98€ 459.03€ | |
| Levitra Soft Tabs | 20mg | 270 + 10 Pills | 521.78€ 496.93€ | |
| Cialis Super Active | 20mg | 60 + 8 Pills | 230.32€ 219.35€ | |
| Kamagra Gold | 100 mg | 120 + 6 Pills | 330.74€ 314.99€ | |
| Cialis Professional | 40mg | 20 Pills | 110.24€ 104.99€ | |
| Kamagra Effervescent Tablets | 100 mg | 63 + 7 Pills | 171.99€ 163.80€ | |
| Levitra Soft Tabs | 20mg | 30 + 2 Pills | 99.17€ 94.45€ | |
| Apcalis SX Oral Jelly | 20mg | 17 + 4 Sachets | 95.52€ 90.97€ |
ED treatment is highly individualized, and thus, the better choice is the one that helps you the most. Price and potential side effects should also be considered when picking an ED drug with your healthcare provider. Erectile dysfunction prevalence in the United States: report from the 2021 National Survey of Sexual Wellbeing, The Journal of Sexual Medicine (2024) Determination that Levitra (vardenafil hydrochloride) tablets, 2.5 milligrams were not withdrawn from sale for reasons of safety or effectiveness, Federal Register (2019) A comparison of the available phosphodiesterase-5 inhibitors in the treatment of erectile dysfunction: a focus on avanafil, Patient Preference and Adherence (2015) Determining the earliest time within 30 minutes to erectogenic effect after tadalafil 10 and 20 mg: a multicenter, randomized, double-blind, placebo-controlled, at-home study, The Journal of Sexual Medicine (2004) Phosphodiesterase-5 (PDE5) inhibitors in the management of erectile dysfunction, Pharmacy & Therapeutics (2013) PDE-5 inhibitors in scleroderma Raynaud phenomenon and digital ulcers: Current status of clinical trials, International Journal of Rheumatology (2011) Phosphodiesterase 5 inhibitors for pulmonary hypertension, Cochrane Database of Systematic Reviews (2019) Phosphodiesterase-5 inhibitors help climbers to achieve new heights, BJUI Internacional (2006) Comparative effectiveness and safety of oral phosphodiesterase type 5 inhibitors for erectile dysfunction: a systematic review and network meta-analysis, European Urology (2013) The effect of phosphodiesterase-type 5 inhibitors on erectile function: an overview of systematic reviews, Frontiers in Pharmacology (2021) Medically accurate: SingleCare’s Medical Review Board analyzes all of our content to confirm it’s in line with current medical advice.
When taken as prescribed, vardenafil and Cialis can be effective ED treatments. However, Cialis may be preferred for its once-daily dosing option, longer duration of action, and approved use for BPH. According to a meta-analysis, tadalafil was found to be the most effective agent for ED, followed by vardenafil. This meta-analysis included 118 different trials and compared seven different medications. All PDE5 inhibitors in the studies were found to have similar safety profiles.
However, one study found that sildenafil, the active ingredient in Viagra, may be the most effective PDE5 inhibitor for ED in the general population. The study noted that while PDE5 inhibitors are generally effective and safe compared to a placebo, more high-quality studies that directly compare these medications are needed. Levitra or Cialis may be more effective, depending on your preferences and other health conditions. Your healthcare provider can help you decide which ED medication is best for you. Most Medicare and commercial insurance plans don’t generally cover ED pills like vardenafil and Cialis.
Therefore, you may have to pay out of pocket for these medications. Some health insurance plans may be more likely to cover Cialis if it’s prescribed for BPH. Still, you may want to contact your pharmacist or insurance company directly about insurance coverage for ED drugs. Vardenafil is a generic medication that may be cheaper than brand-name alternatives. The average retail price may be around $479 for 10 tablets with a strength of 20 mg. Evidence-based: Our content is sourced from reputable U.S.-based healthcare professionals and peer-reviewed research. Trustworthy: All of SingleCare’s content goes through a multi-phase review process by our writers, editors, and Medical Board in order to provide clear and credible information. Vardenafil is a generic medication that treats erectile dysfunction by relaxing blood vessels and increasing blood flow to the penis. Common side effects include headache, flushing, and nasal congestion, while serious side effects are rare but may include vision changes or chest pain. Dosing typically starts at 10 mg taken 25–60 minutes before sexual activity, with adjustments based on effectiveness and tolerance. Vardenafil can interact with nitrates, alpha-blockers, and certain other medications, so always discuss your full medication list with your doctor.
Generic vardenafil offers the same effectiveness as brand-name Levitra at a significantly lower cost.
Vardenafil, sold under the brand name Levitra and available as a generic medication, is a phosphodiesterase-5 (PDE-5) inhibitor used to treat erectile dysfunction (ED) in men. The medication works by relaxing smooth muscle tissue in the penis and increasing blood flow, helping men achieve and maintain an erection during sexual stimulation.
If you experience serious side effects, such as visual changes or sudden hearing loss, seek medical attention immediately. This may not be a complete list of adverse effects that can occur. Please refer to your doctor or healthcare provider to learn more. PDE5 inhibitors like vardenafil and Cialis work by relaxing and widening blood vessels. This effect can help with the intended benefits of these medications, but it can also lead to some unwanted side effects.
Combining vardenafil or Cialis with nitrates, alpha-blockers, or other blood pressure medications (antihypertensives) can lead to a dangerous drop in blood pressure, which may be fatal in severe cases. Vardenafil and Cialis should not be used with guanylate cyclase (GC) stimulators like riociguat for this same reason. Vardenafil and Cialis are both metabolized or processed in the liver. The doses of these drugs may need to be adjusted when taking other drugs that alter certain liver enzymes, such as the CYP3A4 enzyme. Therefore, caution is recommended when mixing vardenafil or Cialis with certain antibiotics, antifungals, and anticonvulsants (seizure medications), among others.
In addition, grapefruit juice may increase the levels of vardenafil and Cialis in the body, which may lead to adverse effects. This is not a complete list of drug interactions. Please consult your doctor before taking these medications. Taking a drug like vardenafil or Cialis may increase the risk of heart attack, stroke, or other heart problems in people with heart disease. The use of vardenafil and Cialis should be avoided in people with a history of unstable angina (chest pain), uncontrolled high blood pressure, stroke, heart attack, arrhythmia, and/or severe heart disease. It does not increase sexual desire and is not effective without sexual arousal.
| Product Type | Average Price per Tablet | Cost Difference | Savings (%) |
|---|---|---|---|
| Brand (Levitra) | $2.50 | N/A | N/A |
| Generic Vardenafil | $1.80 | $0.70 lower | 28% |
| Premium Brands | $3.20 | Higher by $0.70 | +28% |
Generic vardenafil contains the same active ingredient as brand-name Levitra and works identically in the body. The main difference is cost—generic vs brand name drugs are equally effective, but generics typically cost far less.
Cialis is available as a brand-name and generic drug. For 30 tablets with a strength of 5 mg, the average retail price of generic Cialis is around $448. If you’re looking to save on the retail cost of vardenafil or Cialis, you may want to use a SingleCare savings card. You may find that SingleCare helps you save up to 80% on brand-name and generic medications. Another potential alternative is to check out SingleCare’s partnership with Lemonaid Health, where you can get Sildenafil for as little as $2 per pill.
These are the most accurate medication prices at the time of publishing in ZIP code 23666 as of Jan. 30, 2026. The listed price without insurance references the price of brand-name drugs (unless otherwise specified). The listed SingleCare price references the price of generic drugs if available. Vardenafil and Cialis tend to have similar side effects since they’re both in the same drug class.
The most frequently reported side effects include headaches, nasal congestion or a stuffy nose, indigestion, and back pain. In addition, both medications may lead to facial flushing, characterized by redness and libido gummies female uk warmth in the face. Other common side effects of vardenafil are dizziness, flu symptoms, and inflamed sinuses (sinusitis). Other common side effects of Cialis include muscle pain and pain in the arms or legs. Most side effects with these medications are mild and go away on their own. Vardenafil is available in tablet form and reaches peak effectiveness within 30 to 60 minutes of taking a dose.