There are also a few drug interactions you should know about.
The most common Cialis side effects include: Clinical trials show that most side effects are dose-dependent, meaning you’re more likely to get them with higher doses — and remember, Cialis 20 mg is the highest dose of the drug. Allergic reactions to Cialis aren’t common but they’re possible. Swelling of the lips, tongue, or throat Swelling of the lips, tongue, or throat There’s also a risk of priapism or prolonged erections — we’re talking for several hours here. It may sound great if you’re suffering from ED, but prolonged erections can be painful and cause irreversible damage to the penis. If your erection lasts more than four hours, seek medical advice.
You may be more likely to get prolonged, painful erections from Cialis if you have: Anatomic deformations in the penis (like Peyronie’s disease) Anatomic deformations in the penis (like Peyronie’s disease) There’s also a small risk of vision loss. If you notice any vision loss in one or both eyes, stop taking Cialis and seek medical help. This could be a sign of non-arteritic anterior ischemic optic neuropathy (NAION), which is caused by a lack of blood flow to the optic nerve. Another serious side effect includes a sudden decrease in hearing or hearing loss. Again, get medical advice as soon as you notice this. You shouldn’t take Cialis 20 mg (or any dose of the drug) at all if you’re taking nitrates.
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Cialis Generic | 5mg | 180 + 10 Pills | 159.65€ 152.05€ | |
| Cialis Original | 20mg | 34 + 2 Pills | 183.99€ 175.23€ | |
| Cialis Original | 20mg | 48 + 4 Pills | 224.69€ 213.99€ | |
| Cialis Generic | 10mg | 180 + 8 Pills | 236.88€ 225.60€ | |
| Cialis Original | 20mg | 4 Pills | 41.99€ 39.99€ | |
| Cialis Soft Tabs | 20mg | 180 + 8 Pills | 353.17€ 336.35€ | |
| Cialis Professional | 40mg | 20 Pills | 110.24€ 104.99€ | |
| Cialis Generic | 60mg | 270 + 10 Pills | 443.96€ 422.82€ | |
| Cialis Generic | 2.5mg | 180 + 10 Pills | 154.86€ 147.49€ | |
| Cialis Professional | 40mg | 60 + 2 Pills | 262.32€ 249.83€ |
The combo can cause your blood pressure to drop suddenly, resulting in dizziness, loss of consciousness, or even a heart attack or stroke.
| Condition | Caution or Avoid Use | Reason |
|---|---|---|
| Nitrate medication use | Do not take together | Risk of severe hypotension |
| Severe liver impairment | Consult doctor before use | Metabolism issues |
| Severe kidney impairment | Dose adjustment needed | Altered drug clearance |
| Heart disease | Medical evaluation recommended | Potential cardiovascular risk |
Nitrates can be found in medications like isosorbide dinitrate or isosorbide mononitrate, which are used to treat prevent angina caused by heart disease.
For ED — which is when you struggle to get or keep an erection — Cialis works by dilating the blood vessels in the penis, which leads to a firmer erection. Cialis — 20 mg or otherwise — doesn’t just give you an erection, though. Some form of sexual stimulation is required to get hard. Cialis 20 mg may be a more effective treatment for ED than the 10 mg version. Clinical trials found that 68 to 77 percent of men taking 10 mg Cialis were able to have penetrative sex with their partner.
Of those taking 20 mg Cialis, 76 to 85 percent were able to have penetrative sex. But not all research agrees cialis buy cheap — a smaller daily dose may be just as effective as the as-needed Cialis treatment. A systematic review and meta-analysis examined six randomized controlled trials involving more than 1,500 people and compared an as-needed tadalafil treatment to a once-a-day dose. The results showed that both treatments were about equally effective. While Cialis works similarly to Viagra®, Cialis lasts longer in your body. Also, watch out for recreational drugs that contain nitrates, like “poppers.” You also shouldn’t take Cialis if you take medications called guanylate cyclase stimulators, such as riociguat, which treats pulmonary hypertension.
You could be having a life-threatening side effect. Stop using this medicine and call your doctor at once if you have: a light-headed feeling, like you might pass out; a light-headed feeling, like you might pass out; an erection is painful or lasts longer than 4 hours (prolonged erection can damage the penis); an erection is painful or lasts longer than 4 hours (prolonged erection can damage the penis); ringing in your ears or sudden hearing loss; or ringing in your ears or sudden hearing loss; or heart attack symptoms - chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating. heart attack symptoms - chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating. muscle pain, back pain, pain in your arms, legs, or back. This is not a complete list of side effects and others may occur.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Tell your doctor about all your current medicines and any you start or stop using, especially: medicines to treat erectile dysfunction or pulmonary arterial hypertension; medicines to treat erectile dysfunction or pulmonary arterial hypertension; antiviral medicine to treat hepatitis C or HIV/AIDS; antiviral medicine to treat hepatitis C or HIV/AIDS; drugs to treat high blood pressure or a prostate disorder; or drugs to treat high blood pressure or a prostate disorder; or Other drugs may interact with tadalafil, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide. Cialis (tadalafil) and Viagra (sildenafil) are both prescription drugs used to treat erectile dysfunction (ED), but taking them together is generally not recommended. If you’re taking alpha-blockers (like doxazosin, tamsulosin, or alfuzosin) — which mainly treat high blood pressure or BPH — or CYP3A4 inhibitors (like the antibiotic erythromycin
| Patient Type | Recommended Use | Timing | Notes |
|---|---|---|---|
| Adult men with ED | 10-20mg as needed | 30 minutes to 2 hours prior | Max 1 tablet per day |
| BPH or combined ED/BPH | 5-10mg once daily | Same time daily | Consistent timing recommended |
| Elderly patients | Start on lower dose (5mg) | As directed | Adjust based on tolerability |
| Patients with liver impairment | Lower dose as advised | Under medical supervision | Dose adjustments necessary |
and the antifungal medication ketoconazole), which treat a wide variety of conditions, you may be prescribed a low dose of Cialis—probably not the 20 mg kind.
Mixing these medications can lead to dangerously low blood pressure and a higher risk of side effects. When used alone, Cialis may cause small reductions in blood pressure, but if used with nitrates or guanylate cyclase stimulators like riociguat (brand name: Adempas) your blood pressure may dangerously drop. Do not use these drugs with Cialis. You could get dizzy, faint, or have a heart attack or stroke. Cialis vs Viagra - What's the difference between them?
Why does Cialis take at least 12-14 hours to work? Is taking Cialis 40 mg daily safe? Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Cialis only for the indication prescribed. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. You might have seen Cialis® — the popular erectile dysfunction (ED) medication — available in doses ranging from 2.5 mg to 20 mg. It’s unclear whether it’s safe to take Cialis 20 mg or any dose of the drug with other PDE5 inhibitors, such as: Tell your prescribing healthcare provider about the medications or supplements you’re taking before trying Cialis. Beyond medications, watch out for how much you drink when you’re taking Cialis.
| Region | Average Price (USD) per Tablet | Purchasing Options | Note |
|---|---|---|---|
| US | $20 - $30 | Pharmacies, online suppliers | Prescription required |
| Europe | €15 - €25 | Local pharmacies, online pharmacies | Varies by country |
| Asia | $10 - $20 | Online pharmacies, local markets | Verify authenticity |
| Online (Global) | $10 - $40 | Major online retailers | Beware of counterfeit products |
If you have five or more alcoholic drinks, you may experience: And a weird one to watch out for: grapefruit and Cialis.
Some side effects have the same likelihood in both doses, such as flushing and limb pain. If the side effects of Cialis 20 mg are too much, a healthcare provider may reduce your dose. If this is a particularly annoying side effect of other ED medications, switching to Cialis may be the answer. A 2017 systematic review and meta-analysis compared sildenafil (the generic of Viagra) and tadalafil. It found that tadalafil caused lower rates of flushing.
Muscle aches and back pain were more common in tadalafil than sildenafil, though. Overall, tadalafil and sildenafil had similar efficacy and safety, but men and their partners preferred tadalafil. You can learn more about the two ED treatments in our Cialis vs. Viagra guide. As with any medication, Cialis comes with possible side effects. A 2020 study on rats found that grapefruit juice inhibits tadalafil metabolism — remember, that’s the active ingredient in Cialis.
In fact, Cialis is known as the “weekend pill” for its long half-life. Because you can pop one pill and have sex whenever you like over the next 36 hours (give or take a few hours), it offers more spontaneity. In comparison, avanafil only lasts up to six hours, and Viagra only lasts up to four hours. Clinical trials show that Cialis is effective for various severities and types of ED, including difficult-to-treat ED. If you find Cialis 10 mg isn’t working, a 20 mg tablet might do the trick.
You don’t need to take it every day. Depending on your preference and lifestyle, you may not want to take Cialis day in and day out. In fact, the 20 mg dose of Cialis should only be taken as needed. Side effects of Cialis are usually mild and should go away on their own — although they may be worse with higher doses. For example, in clinical trials, 11 percent of people taking tadalafil 10 mg got a headache, whereas 15 percent of those taking tadalafil 20 mg got a headache. This can lead to you having more tadalafil in your system, which can increase your risk of side effects.
You can learn more about what to avoid in our guide to tadalafil interactions.
Finally, tell a healthcare provider about any medical conditions you have before taking Cialis so they can determine whether it’s safe for you.
Cialis 20 mg is an effective erectile dysfunction treatment, but so are the lower doses of the drug. Below, we’ll cover what Cialis 20 mg is used for, the benefits and side effects of this dose of Cialis, and how it compares to other strengths. Cialis is a brand name for tadalafil, a widely prescribed ED medication. Benign prostatic hyperplasia (BPH) or an enlarged prostate Benign prostatic hyperplasia (BPH) or an enlarged prostate Other forms of tadalafil are used to treat pulmonary arterial hypertension, a type of high blood pressure in the lungs, but Cialis is not prescribed for this condition. Cialis doses include 2.5 mg, 5 mg, 10 mg, and 20 mg.
You can take Cialis on an as-needed basis and pop a pill before sex, or you can take a daily dose of Cialis so you’re always ready for action. If you’re taking it as needed, you’ll likely be prescribed 5 mg, 10 mg, or 20 mg. The 10 mg strength is the typical starting dose, and it can be adjusted up or down depending on efficacy and side effects. But you won’t be taking 20 mg of Cialis daily. The lower doses of 2.5 mg and 5 mg are the daily doses of Cialis. Heart problems like angina (chest pain caused by reduced blood flow to the heart), heart disease, or irregular heartbeats Heart problems like angina (chest pain caused by reduced blood flow to the heart), heart disease, or irregular heartbeats Cialis is available in a range of doses.