Before taking sildenafil, tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. See the Interactions section for more details.
Do not take sildenafil unless it has been canadian sildenafil citrate prescribed to you by a healthcare provider.
| Parameter | Description | Typical Values | Notes |
|---|---|---|---|
| Absorption | Time to peak plasma concentration (Tmax) | 30-120 minutes | Taken on an empty stomach for faster absorption |
| Bioavailability | Percentage absorbed into bloodstream | 40% | Affected by food intake |
| Half-life | Duration for plasma concentration to reduce by half | 4 hours | Determines dosing frequency |
| Metabolism | Liver enzyme involved | CYP3A4 | Also metabolized by CYP2C9 |
Do not share sildenafil with other people, even if they have the same condition as you. Keep sildenafil out of the reach of children.
| Side Effect | Frequency | Severity | Management Suggestions |
|---|---|---|---|
| Headache | Common | Mild | Analgesics, hydration |
| Visual disturbances | Less common | Mild-moderate | Discontinue use if persistent |
| Dizziness | Common | Mild | Sit or lie down, avoid driving |
| Priapism | Rare | Severe | Seek immediate medical attention |
| Hearing loss | Very rare | Severe | Discontinue medication, seek help |
If you keep sildenafil oral liquid in a refrigerator, make sure to keep it away from children who also use the refrigerator. Sexual activity can put extra strain on your heart, which may be unsafe for people with certain health problems, such as a recent heart attack.
Doctor of Medicine - Ludwig-Maximilians-University, 2014 Doctor of Medicine - Ludwig-Maximilians-University, 2014 Board Certified Medical Affairs Specialist - Accreditation Council for Medical Affairs, 2024 Board Certified Medical Affairs Specialist - Accreditation Council for Medical Affairs, 2024 Dr. Gussone has contributed widely to consumer health news media, including NBC News TODAY and NBC Nightly News, and has written about his own weight loss journey for CNN. Dr. Gussone has contributed widely to consumer health news media, including NBC News TODAY and NBC Nightly News, and has written about his own weight loss journey for CNN. Dr.
Gussone discovered his passion for creating medical content and educating the public about health while working with CNN’s Dr. Sanjay Gupta. He realized that the media could deliver essential health information to millions, surpassing the reach of one-on-one care in a clinical setting. Scuba diving, traveling, cinema, and perfume making Scuba diving, traveling, cinema, and perfume making Erectile dysfunction is a condition in which you have trouble getting or keeping an erection firm enough for satisfying sex. Erectile dysfunction affects as many as 30 million men in the United States.
Premature ejaculation (PE) is a sexual dysfunction characterized by a short ejaculatory latency, a perceived lack of control about the timing of ejaculation, and distress and interpersonal difficulty related to ejaculating too quickly. Low testosterone or testosterone deficiency, also known as hypogonadism, is a condition in which patients develop symptoms such as low sex drive, erectile dysfunction (ED), and fatigue because the body doesn’t produce enough testosterone. Though many men don’t like to talk about it, ejaculation problems are very common. Some of the most common issues include premature, delayed, or retrograde ejaculation. Your pelvic floor is a lot like plumbing in your home: you never really think about it unless something goes wrong. Talk to your healthcare provider to see if your heart is strong enough for sex. If you feel chest pain, dizziness, or nausea during sex, stop and contact your healthcare provider right away.
Sildenafil does not protect against sexually transmitted infections, including HIV. Sildenafil belongs to a group of medicines, known as phosphodiesterase-5 (PDE-5) inhibitors, which are used to treat erectile dysfunction or pulmonary arterial hypertension. You should not take more than one PDE-5 inhibitor medicine. Medicines in this group include avanafil (Stendra), sildenafil (Viagra, Revatio, and others), tadalafil (Cialis and others), and vardenafil (Levitra, Staxyn). Use an accurate measuring device to measure your dose of sildenafil oral liquid.
A household spoon is not an accurate measuring device and may cause you to take the wrong dose. Ask your pharmacist to recommend an appropriate measuring device.
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Tell your healthcare provider about all of your health conditions and any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. This will help them determine if sildenafil is right for you. In particular, make sure that you discuss any of the following.
Tell your healthcare provider if you have any of the following.
When you think of male sexual dysfunction, concerns like erectile dysfunction (ED) or premature ejaculation (PE) probably come to mind first. But there’s another sex-related issue that’s more common in men than you might expect: difficulty orgasming. Sildenafil is commonly used for the following conditions. Erectile dysfunction, a condition where you have trouble getting or keeping an erection Pulmonary arterial hypertension, a condition where you have high blood pressure in the blood vessels that carry blood from your heart to your lungs Sildenafil may also be used for other conditions as determined by your healthcare provider. Sildenafil works by blocking an enzyme in the body called PDE5, which helps relax certain blood vessels.
For erectile dysfunction, it increases blood flow to the penis when aroused. This makes it easier to get and keep an erection. For pulmonary arterial hypertension, sildenafil relaxes sildenafil 45 mg chewable tablets the blood vessels in the lungs. This lowers blood pressure and reduces strain on the heart. 10 mg/mL powder for oral suspension 20 mg, 25 mg, 50 mg, 100 mg oral tablets Sildenafil is also available in an injectable form that is usually given by a healthcare provider in a hospital or clinic.
Sildenafil oral tablets should be stored at room temperature, between 68 F to 77 F (20 C to 25 C). It can be exposed to temperatures between 59 F to 86 F (15 C to 30 C) for shorter periods of time, such as when transporting it. Sildenafil oral liquid should be stored at room temperature below 86 F (30 C) or in the refrigerator, between 36 F to 46 F (2 C to 8 C). Throw away any remaining liquid 60 days after it has been mixed for you by a pharmacist or healthcare professional. Sildenafil injection is usually given by a healthcare provider in a hospital or clinic. Heart problems, such as heart rhythm problems, chest pain, or heart failure Heart attack, stroke, or heart surgery within the past six months High blood pressure that is still too high despite taking medicines for it Peyronie's disease, or a penis with an abnormal curve or shape An erection lasting longer than four hours A blood disorder, such as sickle cell anemia An inherited eye disease called retinitis pigmentosa Vision loss, or a problem with the nerve between your eyes and brain (optic nerve) Health conditions or factors that raise the risk of optic nerve problems, such as diabetes, high cholesterol, smoking, being older than 50, or having a “crowded disc,” which is something an eye doctor may see in an eye exam Pulmonary veno-occlusive disease, a condition where blood vessels in the lungs are blocked It is not known if or how sildenafil could affect pregnancy or harm an unborn baby. Tell your healthcare provider if you are or plan to become pregnant.
You will not store it at home. The most common side effects of sildenafil are listed below. These side effects may vary depending on the condition that is being treated. Tell your healthcare provider if you have any of these side effects that bother you. Pain in your muscles, back, arms, or legs There may be other side effects of sildenafil that are not listed here.
Contact your healthcare provider if you think you are having a side effect of a medicine. In the U.S., you can report side effects to the FDA at or by calling 800-FDA-1088. In Canada, you can report side effects to Health Canada at or by calling 866-234-2345. While less common, the most serious side effects of sildenafil are described below, along with what to do if they happen. Sildenafil may cause allergic reactions, which can be serious.
Stop taking sildenafil and get help right away if you have any of the following symptoms of a serious allergic reaction. Swelling of the face, lips, mouth, tongue, or throat Itching, skin rash, or pale red bumps on the skin called hives Sildenafil may cause an unwanted erection that is persistent, painful, and that may occur without sexual arousal. Permanent damage to the penis may occur if priapism is not treated quickly. Stop taking sildenafil and get emergency help if you have any of the following symptoms of priapism. Erection lasting for more than four hours Erection that is unrelated to sexual stimulation Sildenafil can cause mild, temporary vision changes such as seeing a blue tint, abnormal colors, blurry vision, or sensitivity to light. Tell your healthcare provider if you are breastfeeding or plan to breastfeed.
| Interacting Drug/Class | Effect on Sildenafil | Clinical Significance | Recommendations |
|---|---|---|---|
| Nitrates | Potentiates vasodilation | Risk of severe hypotension | Avoid concomitant use |
| CYP3A4 inhibitors (e.g., Ritonavir) | Increase sildenafil plasma levels | Risk of increased side effects | Reduce dose or avoid |
| Alpha-blockers | Additive blood pressure lowering | Hypotension | Use with caution, monitor BP |
| CYP3A4 inducers (e.g., Rifampin) | Decrease sildenafil effectiveness | May reduce efficacy | Adjust dose accordingly |
Your healthcare provider will advise you if you should take sildenafil while breastfeeding. If you take sildenafil after you eat a high-fat meal, such as a burger and fries, it may take longer to start working.
Though rare, some people have reported permanent vision loss. Stop taking sildenafil and get help right away if you have sudden vision loss in one or both eyes. Sudden hearing loss has been reported after taking sildenafil. This may occur sildenafil citrate 200mg price along with dizziness and ringing in the ears. Stop taking sildenafil and get help right away if you have sudden hearing loss or suddenly have trouble hearing as well as usual.
Sildenafil may cause a mild and temporary drop in blood pressure. You may be at a higher risk if you have certain health conditions or take blood pressure medicines. If you feel faint or dizzy, lie down. Tell your healthcare provider right away if you have any of the following symptoms of low blood pressure. You may be at higher risk for this if you take a blood thinner medicine.
Tell your healthcare provider if you get nosebleeds often while taking sildenafil. If your nosebleed is severe or will not stop after applying pressure, get help right away. People who are allergic to any of the following should not take sildenafil. Any of the ingredients in the specific product dispensed Your pharmacist can tell you all of the ingredients in the specific sildenafil products they stock. Sildenafil should not be taken while you are using certain other medicines. Your healthcare provider may recommend limiting or avoiding grapefruit while taking sildenafil.